What is the idiopathic disorder characterized by an unusually high count of red blood cells?

Study for the Funeral National Board Pathology Exam. Tackle multiple choice questions insightfully designed with hints and explanations to ensure your success. Prepare efficiently for your exam!

The idiopathic disorder characterized by an unusually high count of red blood cells is Polycythemia Vera. This condition is a type of blood cancer that results in an overproduction of red blood cells by the bone marrow. The increase in red blood cell mass can lead to a variety of complications, including an increased risk of thrombosis, hypertension, and a ruddy complexion due to increased blood volume and viscosity.

Polycythemia Vera is categorized as a myeloproliferative neoplasm, which means it arises from the clonal proliferation of hematopoietic stem cells. While the exact cause of Polycythemia Vera is often idiopathic (unknown), it is frequently associated with mutations in the JAK2 gene, which plays a critical role in regulating blood cell production. The diagnosis is supported by laboratory findings, showing elevated red blood cell mass, high hemoglobin levels, and sometimes elevated white blood cell and platelet counts.

In contrast, the other conditions listed, such as secondary anemia, aplastic anemia, and hemolytic anemia, involve either a deficiency in red blood cell production, destruction of red blood cells, or are a consequence of other underlying conditions rather than an idiopathic overproduction of red cells. Thus, Polycy

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